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TIEI Extraction’s intelligent extraction engineering system helps safe production in the extraction workshop

The production process of chemically synthesized APIs usually includes multi-step chemical reactions and physical treatment of some materials. These operating units are relatively complex and include steps such as reaction, extraction, decolorization, filtration, crystallization, centrifugation, and drying. The main chemical raw materials required for production, such as sodium hydroxide, sulfuric acid, aluminum trichloride, ammonia and other inorganic compounds, as well as formic acid, diethyl ester, phenol, acetaldehyde, nitrobenzene and other organic compounds, are mostly included in the key supervision List of hazardous chemicals.

In the extraction operation, some water-insoluble organic raw materials are usually used as extraction agents, such as toluene, ether, acetone, ethanol, chloroform, ethyl acetate, etc. Most of these raw materials are flammable, explosive, corrosive or toxic. Therefore, API factories are mostly flammable and explosive Class A factories and warehouses, and the safety risks are very high.

With the maturity of centrifugal extraction technology and the increasing demand for automation in the API industry, the CWL-M new Liquid Liquid Centrifugal Extractor is known for its high extraction efficiency, closed and continuous operation, low solvent consumption, high degree of automation, large processing capacity and small space occupation. With its advantages, it has gradually replaced traditional gravity extraction equipment and become the main body of extraction equipment. The CWL-M new centrifugal extraction process has also been increasingly widely used.

It is worth mentioning that in order to improve the technological level and safety level of API production, Tianyi Extraction has launched an intelligent extraction engineering system with new centrifugal extraction technology as the core. This system responds to the development trend of intelligent manufacturing. TIEI Extraction Intelligent Extraction Engineering System is an intelligent product integrating industrialization, informatization, digitalization and other technologies. Different from traditional extraction workshops, this intelligent extraction engineering system can realize real-time intercommunication of people, products, facilities and equipment, as well as operating data and information, and effectively realize the intelligence of factory facilities and equipment by using Internet of Things technology and big data cloud platform technology. Control, accurately identify factory operations, help customers build safe, green, efficient and energy-saving production plants, thereby improving the economic strength and social benefits of customer factories.

In summary, the management of hazardous chemicals is a very important part of the production of APIs. It involves all aspects of technology, equipment, automation and operation. New technology is an important means to promote production safety, and centrifugal extraction and intelligent extraction engineering systems are the development trend of solute extraction, oil-water separation, and solution washing technology. Its characteristics of closed operation, continuous production, automation, and unmanned operation are in line with the raw materials requirements for drug production safety.